DESCRIPTIONClopidogrel belongs to the class of drugs called antiplatelet drugs. This class of medications that reduce the ability of platelets (specialized blood cells) to stick together, which occurs normally as part of the blood-clotting process. Antiplatelet drugs are used to prevent the formation of blood clots in arteries, when anticoagulants are ineffective.
Clopidogrel used to prevent strokes or heart attacks occurring in people at risk, particularly in those who have had a previous stroke or heart attack.
ORIGINAL USES (ON-LABEL)
Reduction of atherosclerotic events (myocardial infarction, stroke, and vascular death) in patients with atherosclerosis documented by recent stroke, myocardial infarction, or established peripheral arterial disease; prevention of thrombosis following intracoronary stent placement; acute coronary syndromes.
NEWLY DISCOVERED USES (OFF-LABEL)
Kawasaki Disease
MECHANISM OF ACTION
Selectively and irreversibly inhibits ADP-induced platelet aggregation by inhibiting the binding of ADP to its receptors on platelets, thereby affecting ADP-dependent activation of the glycoprotein IIb / IIIa complex, the major site of platelet-fibrinogen binding.
POTENTIAL SIDE EFFECTS
Bleeding from the stomach, intestines, or elsewhere can occur. Other side effects may include nausea, vomiting, abdominal discomfort, constipation, diarrhoea, headache, dizziness, and rashes.
CAUTIONS
- Plavix should not be taken by people with bleeding peptic ulcers or bleeding from other sites.
- It is not recommended for people with severe angina or for those who have had coronary-artery surgery.
- It should be used with caution in people with liver or kidney disease.
Fluvastatin, phenytoin, tamoxifen, tolbutamide, torsemide. Warfarin should not be used with clopidogrel. Anticoagulants: their effects are enhanced by clopidogrel. NSAIDS (including aspirin): may increase the risk of gastrointestinal bleeding.
FOOD INTERACTIONS
Take without regard to meals.
HERBAL INTERACTIONS
Unknown
PREGNANCY AND BREAST-FEEDING CAUTIONS
Pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take Plavix without first talking to your doctor if you are pregnant.
SPECIAL INFORMATION
Should probably replace ticlopidine as an aspirin alternative Inform clinician of signs and symptoms of bleeding, prior to surgery, dental work; inform clinician of sore throat, fever, etc. (consider neutropenia)
Buy Plavix online
Where can I buy Plavix without prescription?Clopidogrel is a prescription drug that comes in 75 mg tablets. It is available on prescription only as tablets for oral use, but the online pharmacy, will sell Clopidogrel without prescription. You may be able to order Plavix from them online and save the local pharmacy markup.
Whether I can pay my Clopidogrel order by Credit Card?
Pharmacies accept credit cards Visa and Mastercard, online checks (ACH), EuroDebit, Wire transfers.
Is the Plavix purchase legal?
Yes, it is legal. You confirm, that buy Plavix tablets only for personal use without the purposes of resale. All medicines are solved for application in the majority of the countries. Generic Clopidogrel should pass any customs house, including American, without problems. If you have problems with customs house, inform pharmacy, they shall repeat (free-of-charge) your Clopidogrel order.
If I'm buying Plavix online for the first time?
Buy Clopidogrel online after comparing prices to your local pharmacy and you'll agree - any drugstore can sell you generic cheap Plavix at a reduced cost.
What is Plavix?
Clopidogrel helps to prevent blood clots.
Clopidogrel helps to prevent blood clots.
BRAND NAME
Plavix
GENERIC NAME
Clopidogrel
CHEMICAL CLASS
Thienopyridine derivative
THERAPEUTIC CLASS
Antiplatelet/Aggregation Inhibitor
Plavix
GENERIC NAME
Clopidogrel
CHEMICAL CLASS
Thienopyridine derivative
THERAPEUTIC CLASS
Antiplatelet/Aggregation Inhibitor
AVAIL FORMS
Tablets — Oral 75 mg.
Tablets — Oral 75 mg.
DOSAGE
Adult
PO 75 mg qd (no dosage adjustments for elderly patients or those with renal impairment); 300 mg loading dose × 1 may be used to provide faster onset of antiplatelet effect.
Adult
PO 75 mg qd (no dosage adjustments for elderly patients or those with renal impairment); 300 mg loading dose × 1 may be used to provide faster onset of antiplatelet effect.
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