DESCRIPTION
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID), which relieves pain and swelling. It is used to treat headaches, muscle aches, backaches, dental pain, menstrual cramps, arthritis, or athletic injuries, and to reduce fever and minor aches due to the common cold or flu.

ORIGINAL USES (ON-LABEL)
Inflammatory diseases, rheumatoid arthritis, mild to moderate pain or fever or dysmenorrhea.

NEWLY DISCOVERED USES (OFF-LABEL)
Kidney stones, lumbar puncture induced headache, membranous nephropathy, periodontitis, renal colic, ureteral stones.

POTENTIAL SIDE EFFECTS
Abdominal cramps, nausea, stomach upset, diarrhea, flatulence, weakness, stomach irritation, blurred vision, ringing in the ears, constipation.

CAUTIONS
  • Not for use if you are allergic to aspirin or other NSAIDs.
  • Not for use if you have active gastric/duodenal ulcer disease.
  • Do not use during third trimester of pregnancy.
  • Ask physician about use if you have the following medical problems: high blood pressure, dehydration, decreased kidney or liver function, history of gastric disease.
  • Elderly are at higher risk of developing side effects.
  • Do not exceed 3200mg/day.
DRUG INTERACTIONS
Aspirin, lithium, methotrexate, digoxin, cyclosporine (nephrotoxicity), diuretics, some anti-hypertensives, and warfarin (bleeding).

FOOD INTERACTIONS
Peak serum concentration decreases with food.

HERBAL INTERACTIONS
Cat's claw, dong quai, evening primrose, feverfew, garlic, ginger, ginkgo, red clover, horse chestnut, green tea, ginseng.

PREGNANCY AND BREAST-FEEDING CAUTIONS
FDA Pregnancy Risk Category B (D if in 3rd trimester). Excreted in breast milk. Consult your doctor.

SPECIAL INFORMATION
Stop taking this drug (with doctor’s approval) approximately 24 to 48 hours prior to surgical or dental procedures, as it affects the body’s ability to form blood clots and may increase bleeding time. In April 2005, the FDA announced the potential addition of a black box warning to the labeling of this class of drugs (NSAIDs), specifically regarding potential serious cardiac events and potentially life-threatening gastric adverse events.

This information refers only to use of the prescription product.

Indomethacin is commonly used for the treatment of PDA but has renal failure as a main side effect. Ibuprofen seems to be efficient in closing the ductus with fewer side effects, but few studies are available in literature regarding its use in preterm infants. A study analyzed data to compare the efficacy and tolerability of ibuprofen and indomethacin for the treatment of PDA administered to preterm infants. Ibuprofen was found to be as efficient as indomethacin and could be an alternative treatment. NSAID treatment was found to affect, at least transiently, renal function. Further studies are needed to assess whether Motrin is really less nephrotoxic than indomethacin. It should be noted that intravenously administered ibuprofen is not commercially available in United States.

Buy Ibuprofen online

Where can I buy Ibuprofen without prescription?
Ibuprofen is a prescription drug that comes in 400 mg, 600 mg tablets. It is available on prescription only as tablets for oral use, but the online pharmacy, will sell Motrin without prescription. You may be able to order Motrin from them online and save the local pharmacy markup.

Whether I can pay my Ibuprofen order by Credit Card?
Pharmacies accept credit cards Visa and Mastercard, online checks (ACH), EuroDebit, Wire transfers.

Is the Motrin purchase legal?
Yes, it is legal. You confirm, that buy Ibuprofen tablets only for personal use without the purposes of resale. All medicines are solved for application in the majority of the countries. Generic Ibuprofen should pass any customs house, including American, without problems. If you have problems with customs house, inform pharmacy, they shall repeat (free-of-charge) your Motrin order.

If I'm buying Motrin online for the first time?
Buy Motrin online after comparing prices to your local pharmacy and you'll agree - any drugstore can sell you generic cheap Ibuprofen at a reduced cost.

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What is Ibuprofen?
Ibuprofen inhibits the production of prostaglandin, a chemical drug in the body responsible for inflammation and pain.
BRAND NAME
Motrin, Ultraprin

GENERIC NAME
Ibuprofen

CHEMICAL CLASS
Propionic acid derivative

THERAPEUTIC CLASS
Pain reliever, anti-inflammatory (nonsteroidal anti-inflammatory [NSAID])
AVAIL FORMS
Tablets — Oral 400 mg, 600 mg.
DOSAGE
Adult
PO 200-800 mg qid, not to exceed 3200 mg/day. (NOTE: Doses <1600 mg/day analgesic only; >1600 mg/day needed for antiinflammatory activity)
Child
PO 20-40 mg/kg/day divided tid or qid.

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