DESCRIPTION
Simvastatin is a cholesterol-lowering drug of the group called “statins” to lower cholesterol used when diet and exercise are not enough. In patients with coronary heart disease and elevated cholesterol, simvastatin is used to reduce the risk of death, stroke, and heart attack. It reduces the amount of cholesterol produced and increases the rate it is removed from the body. Patients with liver or kidney disease should not be given simvastatin because it can cause further damage. Side effects of this drug include gastrointestinal upset, headache, insomnia, dizziness, and fatigue.

ORIGINAL USES (ON-LABEL)
Cardiovascular disease, coronary heart disease prophylaxis, familial combined hyperlipidemia, familial dysbetalipoproteinemia, heterozygous familial hypercholesterolemia, homozygous familial hypercholesterolemia hyperlipidemia, mixed dyslipidemia, primary hypercholesterolemia, stroke prophylaxis.

NEWLY DISCOVERED USES (OFF-LABEL)
Membranous nephropathy, multiple sclerosis, peripheral artery disease, postmenopausal osteoporosis.

POTENTIAL SIDE EFFECTS
Headache, diarrhea, upset stomach, flatulence, rash, muscle aches.

PRECAUTIONS
Past liver disease, alcoholism, severe acute infections, trauma, hypotension, uncontrolled seizure disorders, severe metabolic disorders, electrolyte imbalances.

DRUG INTERACTIONS
Warfarin, cyclosporine, gemfibrozil, niacin, erythromycin, clofibrate, clarithromycin, ketoconazole, itraconazole, protease inhibitors, digoxin.

FOOD INTERACTIONS
Grapefruit juice. Avoid excessive intake of alcohol.

HERBAL INTERACTIONS
St. John's wort

PREGNANCY AND BREAST-FEEDING CAUTIONS
FDA Pregnancy Risk Category X. Simvastatin should not be used during breast-feeding.

SPECIAL INFORMATION
A study in Bone from the University of Siena, Italy reported that 30 postmenopausal hypercholesterolemic women were treated with simvastatin for 12 months and 30 normocholesterolemic postmenopausal women provided control data. The difference between the two groups was significant for bone mineral density at the spine and hip, with the treated women showing increases at both sites, and a positive effect shown for simvastatin.

An article in Pharmacoepidemiological Drug Safety reported on a study from Brigham and Women's Hospital in Boston that examined the relationship between statin use and bone density among postmenopausal women. They did a survey of postmenopausal women who had bone densitometry and agreed to a telephone interview about their OP risk factors, use of hormone replacement therapy, and osteoporosis medications and statin exposure. Of 339 women studied, 162 were current or past users of statins. Statin users has significantly higher body mass index and rates of thiazide use and were more likely to abstain from alcohol. Researchers found that statin use was associated with significantly higher bone mineral density at the hip compared to non-users.

Buy Zocor online

Where can I buy Zocor without prescription?
Simvastatin is a prescription drug that comes in 5 mg, 10 mg, 20 mg tablets. It is available on prescription only as tablets for oral use, but the online pharmacy, will sell Simvastatin without prescription. You may be able to order Zocor from them online and save the local pharmacy markup.

Whether I can pay my Simvastatin order by Credit Card?
Pharmacies accept credit cards Visa and Mastercard, online checks (ACH), EuroDebit, Wire transfers.

Is the Zocor purchase legal?
Yes, it is legal. You confirm, that buy Zocor tablets only for personal use without the purposes of resale. All medicines are solved for application in the majority of the countries. Generic Simvastatin should pass any customs house, including American, without problems. If you have problems with customs house, inform pharmacy, they shall repeat (free-of-charge) your Simvastatin order.

If I'm buying Simvastatin online for the first time?
Buy Simvastatin online after comparing prices to your local pharmacy and you'll agree - any drugstore can sell you generic cheap Zocor at a reduced cost.

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What is Zocor?
This drug inhibits an enzyme (HMG-CoA reductase) that is an important factor in the production of cholesterol.
BRAND NAME
Zocor

GENERIC NAME
Simvastatin

CHEMICAL CLASS
HMG-CoA reductase enzyme

THERAPEUTIC CLASS
HMG-CoA reductase inhibitor; antilipemic
AVAIL FORMS
Tablets — Oral 5 mg, 10 mg, 20 mg.
DOSAGE
Adult
PO 5-10 mg qd in pm initially, usual range 5-40 mg/day qd in pm; max daily dose 80 mg; dosage adjustments may be made in 4-wk intervals.

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